CompletedNot Applicable

Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study

United States34 participantsStarted 2017-02-10

Plain-language summary

The purpose of this pilot study is to describe the relationship of regional cerebral oximetry and cytoximetry, measured using near-infrared spectroscopy, with seizure activity in the periictal period in children with epilepsy.

Who can participate

Age range7 Years

SexALL

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Inclusion criteria

✓. Pediatric epilepsy patients who can provide assent (lower limit age 7).
✓. Diagnosis of partial (focal) epilepsy and/or frequent interictal spike activity on EEG.
✓. Clinical EEG supporting diagnosis of partial(focal) epilepsy and/or frequent interictal spike activity

Exclusion criteria

✕. History of unrepaired or palliated congenital cyanotic heart disease
✕. History of traumatic head injury or head wounds to the extent that precludes safe and consistent placement of NIRS-EEG probes.
✕. Guardian does not give consent or patient is unable to consent/assent to participate in the study
✕. Clinical care provider or investigator determines the patient is not appropriate candidate for the study
✕. Lack of current seizure care plan in Children's Hospital medical record
✕. Known sensitivity or allergy to EEG gel

What they're measuring

Change in CCO redox state and oxygen saturation

Timeframe: 1 week

Trial details

NCT IDNCT03054961

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06-07

View on ClinicalTrials.gov More Epilepsies, Partial trials