CompletedNot Applicable

Efficiency of PRP on Acellular Dermal Matrix Application in the Treatment of Multiple Adjacent Gingival Recessions

12 participantsStarted 2008-07-01

Plain-language summary

The aim of this study was to evaluate the effectiveness of platelet rich plasma (PRP) combined with coronally advanced flap plus acellular dermal matrix application (CAF+ADM) in the treatment of multiple adjacent gingival recessions (MAGRs). 12 patients with 84 Miller Class I or II recession defects were participated. Sites were randomly assigned into CAF+ADM+PRP or CAF+ADM groups. Gingival recession depth (GRD), recession width (GRW), width of keratinized tissue (WKT), creeping attachment (CRA), root coverage (RC) as well as plaque index, gingival index, probing depth (PD), and clinical attachment level (CAL) were recorded at baseline and 3rd,6th and 12th months postoperatively. The data were analyzed statistically.

Who can participate

Age range34 Years – 57 Years

SexALL

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Inclusion criteria

✓. Clinical diagnosis of the presence of at least three multiple adjacent Miller class I or II recessions on both sides of the same maxillary or mandibular arch
✓. must be able to have 2 mm-high keratinized tissue apical to the root exposures;
✓. must be able to have no systemic diseases that could influence the outcome of the therapy;
✓. must be able to have a full-mouth plaque score of 20% (O'Leary et al. 1972);
✓. must be non-smoker;
✓. must be not pregnant.

What they're measuring

Root coverage (RC)

Timeframe: The change in RC at 3rd month to 12th month

Trial details

NCT IDNCT03043638

SponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2011-06-20

View on ClinicalTrials.gov More Gingival Recession, Generalized trials