CompletedNot Applicable

Genomic Sequencing in Patients With HCM Undergoing Septal Myectomy

United States25 participantsStarted 2018-08-30

Plain-language summary

Investigators aim to use comparative exome and/or genome sequencing to discover causative molecular lesions for phenotypes hypothesized to be caused by somatic mutations. For this study, investigators have targeted hypertrophic cardiomyopathy.

Who can participate

Age range18 Years – 100 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient is 18 years and older has a clinical diagnosis of hypertrophic cardiomyopathy. * Patient scheduled for clinically-indicated myomectomy. * Patient has a negative family history of hypertrophic cardiomyopathy * Patient is willing to receive results of secondary variant screen Exclusion Criteria: * Pregnant * Inability to give informed consent

What they're measuring

Genetic causes of HCM in patients without a strong family history of the condition

Timeframe: one year

Trial details

NCT IDNCT03043209

SponsorThe Cleveland Clinic

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-12-04

View on ClinicalTrials.gov More Hypertrophic Cardiomyopathy trials