Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension

Inclusion Criteria: * Known diagnosis of intracranial hypotension, established by the following criteria: the presence of orthostatic headache, and one or more of the following criteria: prior CSF opening pressure ≤6 cmH20, demonstration of an active spinal CSF leak on prior spine imaging, or cranial MRI changes of intracranial hypotension.15 * Ability to provide informed consent. * Expected ability to complete standard-of-care procedures (lumbar puncture and epidural patching) Exclusion Criteria: * Known contraindication to MRI (pacemaker, MRI incompatible hardware, etc.) * Severe claustrophobia or other condition requiring the need for anxiolysis, sedation, or any other medication for MRI scanning * Inability or expected inability to complete study interventions as scheduled * Any known contraindication to standard-of-care procedures (e.g. coagulopathy, allergic reaction to required medication, lack of vascular access, etc.)