CompletedNot Applicable

Decreasing Antibiotic Use in Infants With Suspected Ventilator-associated Infection

United States555 participantsStarted 2017-03-20

Plain-language summary

This is a prospective study with three specific aims: (1) To convene a consensus conference to develop a guideline for antibiotic use in infants (age \< 3 yrs) with suspected ventilator-associated infection; (2) To evaluate outcomes before and after implementation of the antibiotic guideline; (3) To evaluate changes in the tracheal microbiome over the course of mechanical ventilation

Who can participate

Age range3 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age newborn -- 3 years in the Pediatric ICU * on invasive mechanical ventilation \> 48 hours * evaluation for ventilator-associated infection that includes respiratory secretion cultures and microscopic evaluation of the gram-stained specimen * antibiotics initiated for suspected ventilator-associated or other infection Exclusion Criteria: * Immune compromise --Other positive cultures (blood, urine, etc.) for which antibiotic continuation is appropriate

What they're measuring

Pediatric ICU-free days at 28 days

Timeframe: 28 days after study enrollment

Trial details

NCT IDNCT03041207

SponsorVirginia Commonwealth University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-04-30

View on ClinicalTrials.gov More Ventilator Associated Pneumonia trials