Influence of Instaflex Advanced Supplement on Joint Function

Inclusion Criteria: * Male or female adult * Age 50-75 years * Self-reported history (\>3 months) of joint discomfort in the knees. NOTE: the severity of knee discomfort will be determined through a questionnaire called the WOMAC, and should be at least 2 points (indicating mild knee discomfort or greater). * No history of regular use of non-steroidal anti-inflammatory drugs (NSAIDs) use (e.g., ibuprofen, aspirin) during the previous two weeks, and willingness to avoid the use of NSAIDs during the 12-week study. * Not on other medications (e.g., analgesic gels, arthritis medications, other anti-inflammatory drugs) or supplements (in particular, glucosamine and chondroitin) for joint discomfort during the previous two weeks, and a willingness to avoid use of these during the 12-week study. * No serious medical problems (current cancer case, severe rheumatoid arthritis, recent heart attack, recent stroke, congestive heart failure, ulcers, kidney disease, or other disease that would interfere with study participation). * No psychiatric disorder or other condition that might interfere with self-assessment ability. * Willingness to follow all study procedures including randomization to one of two groups, and to stay weight stable during the study. Exclusion Criteria: * Inability to comply with study requirements including avoidance of NSAIDs, other anti-inflammatory medications, or discomfort supplements. * Current diagnosis of cardiovascular disease, cancer (except for non-mel…