CompletedNot Applicable

Predictive Value of Renal Venous Flow Profiles for Adverse Outcomes in Right Heart Failure

Germany421 participantsStarted 2016-11

Plain-language summary

Predictive value of renal venous flow profiles for adverse outcomes in patients with right heart failure

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Pulmonary hypertension cohort: Exclusion Criteria: * CKD stage 5 (KDIGO) * pre-existing acute kidney injury (acute kidney injury was defined as an increase in serum creatinine by ≥ 0.3 mg/dl within 48 hours or to ≥ 1.5 times baseline within the prior 7 days, as determined by all available serum creatinine values from hospital and outpatient medical records within the previous 90 days) * Non-end stage renal disease patients with extracorporeal or peritoneal ultrafiltration for treatment of diuretic-resistant fluid overload * Patients with primary kidney disease (e.g., glomerulonephritis, autosomal dominant polycystic kidney disease, postrenal obstruction) * solid-organ transplant recipients * use of non-steroidal inflammatory drugs within 72 hours before right heart catheterization Heart failure cohort: Exclusion criteria same as in the discovery cohort except pre-existing acute kidney injury * Patients with mechanical assist devices are excluded

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Rate of pulmonary hypertension-related morbidity and all-cause mortality (pulmonary hypertension cohort)

Timeframe: 1 year post-discharge

First occurrence of worsening heart failure and first occurrence of need for renal replacement therapy (heart failure cohort)

Timeframe: 1 year post-discharge

Trial details

NCT IDNCT03039959

SponsorUniversity of Giessen

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-03-30

View on ClinicalTrials.gov More Pulmonary Hypertension trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.