CompletedNot Applicable

Hemodynamic Parameters Changes in the Course of Hemodialysis Sessions in Patients With Intradialytic Hypertension

Israel22 participantsStarted 2016-11

Plain-language summary

While the exact pathogenesis of Intradialytic hypertension remains to be determined, several mechanisms were proposed to be involved. The main factors to determine the arterial blood pressure are the peripheral vascular resistance and cardiac output. The assumption is that the increase of blood pressure is related to the increase in peripheral vascular resistance during the dialysis session, due to fluid removal and fast reduction of the intravascular volume reduction. Using the NICAS device (Non-Invasive Cardiac System), the hemodynamic profile in patients with intradialytic hypertension will be evaluated

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Intradialytic hypertension at least once weakly * Age older than 18 years * Chronic hemodialysis treatment more than 3 months * Stable dialysis treatment conditions * Stable antihypertensive treatment for the last 4 weeks prior the study * Patients able and agree to sign the consent form. Exclusion Criteria: * Recent changes in the antihypertensive treatment * Recent acute cardiovascular event

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Peripheral vascular resistance (dyne/sec/cm5)

Timeframe: During 3 consecutive hemodialysis session in one week

Stroke volume (ml)

Timeframe: During 3 consecutive hemodialysis session in one week

Stroke index (ml/m2)

Timeframe: During 3 consecutive hemodialysis session in one week

Cardiac output (l/min)

Timeframe: During 3 consecutive hemodialysis session in one week

Cardiac index (l/min/m2)

Timeframe: During 3 consecutive hemodialysis session in one week

Heart rate (bpm)

Timeframe: During 3 consecutive hemodialysis session in one week

blood pressure (mm/Hg)

Timeframe: During 3 consecutive hemodialysis session in one week

Trial details

NCT IDNCT03038165

SponsorWestern Galilee Hospital-Nahariya

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2017-12

View on ClinicalTrials.gov More Intradialytic Hypertension trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Peripheral vascular resistance (dyne/sec/cm5)

Timeframe: During 3 consecutive hemodialysis session in one week

Stroke volume (ml)

Timeframe: During 3 consecutive hemodialysis session in one week

Stroke index (ml/m2)

Timeframe: During 3 consecutive hemodialysis session in one week

Cardiac output (l/min)

Timeframe: During 3 consecutive hemodialysis session in one week

Cardiac index (l/min/m2)

Timeframe: During 3 consecutive hemodialysis session in one week

Heart rate (bpm)

Timeframe: During 3 consecutive hemodialysis session in one week

blood pressure (mm/Hg)

Timeframe: During 3 consecutive hemodialysis session in one week