Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibri… (NCT03032965) | Clinical Trial Compass
CompletedPhase 2
Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation
United States131 participantsStarted 2011-10
Plain-language summary
The purpose of this study is to determine if additional ablation during the first procedure as the result of the ability to medically induce quiet atrial arrhythmias will improve clinical outcome in patients with atrial fibrillation thus decreasing the need for additional ablation procedures.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Patients \>18 and \<75 who are able to give informed consent undergoing atrial fibrillation ablation procedure.
. Paroxysmal Atrial fibrillation lasting = 7 days which is self-terminating. It is considered recurrent if two or more episodes occur.
. Failure or unwilling to take class I or III anti-arrhythmic drugs
Exclusion criteria
. History of asthma
. Patients with severe coronary artery disease, stable/unstable angina, or ongoing myocardial ischemia
. Previous cardiac surgery ( excluding CABG and mitral valve surgery)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
. Symptomatic congestive heart failure including but not limited to NYHA III/IV and/or documented ejection fraction \<40% measured by acceptable cardiac testing,
. Left atrial diameter \>55mm
. Moderate to severe mitral or aortic valve disease
. Myocardial infarction within three months of enrollment
. Congenital heart disease where it increases the risk of an ablative procedure