CompletedNot Applicable

n-3 PUFAs, Irisin and Maternal Glucose Metabolism From Pregnancy to Postpartum

China1,122 participantsStarted 2017-03-10

Plain-language summary

This study aims to investigate the associations of maternal nutritional status during pregnancy and postpartum periods with postpartum abnormal glucose metabolism in Guangzhou pregnant women. Additionally, it seeks to explore the relationships between maternal nutritional status (pre- and postnatal) and offspring health outcomes, including physical growth, neurodevelopment, and common childhood diseases.

Who can participate

Age range20 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 20 and 45 years (inclusive). * Singleton pregnancy. * Free from the following pre-pregnancy or pregnancy-related conditions: pregestational diabetes mellitus, cardiovascular disease, thyroid disease, hematological disease, polycystic ovary syndrome, infection during pregnancy, or mental disorder. \- Note: Women who meet all of the above criteria are eligible for the study, regardless of whether they have gestational diabetes mellitus (GDM) or not.

What they're measuring

Maternal glucose metabolism

Timeframe: Gestation (24-28 weeks) and, for fasting glucose, also at 42 days postpartum.

Offspring physical growth and development

Timeframe: Birth, 6 months, 2 years, 3-4 years, and 5 years of age.

Offspring neuropsychological development

Timeframe: 2 years, 3-4 years, and 5 years of age.

Offspring allergic diseases

Timeframe: 6 months, 2 years, and 3-4 years.

Trial details

NCT IDNCT03023293

SponsorSun Yat-sen University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-31

View on ClinicalTrials.gov More Gestational Diabetes Mellitus trials