CompletedNot Applicable

Gingival Recession Treatment With Concentrated Growth Factor(CGF)

19 participantsStarted 2013-02

Plain-language summary

Platelet concentrates(PC) are used in the field of periodontology and implantology for the content necessary key cells and growth factors to accelerate healing and to provide regeneration. Concentrated Growth Factors(CGF) is defined as an innovative method or a new generation PC. The purpose of this clinical study was to evaluate the clinical effectiveness of Concentrated Growth Factor(CGF) membrane with coronally advanced flap(CAF) procedure's and subepithelial connective tissue graft(SCTG) with CAF in the treatment of Miller class I gingival recessions (GR).

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age≥18 * systemically and periodontally healthy non-smoker patients * multiple, adjacent, bilaterally Miller class I * recession depth ≥2 and ≤5 mm, probing depth≤3 mm, located lateral, canine or premolars on same arch(maxilla or mandibula) * identifiable cemento-enamel junction * absence caries or restoration on buccal surface, endodontic treatment or problem * palatal donor tissue thickness ≥3 mm for SCTG Exclusion Criteria: * patients have smoking habit or systemic diseases that might be contraindication for periodontal surgery * the presence of using medication affect that blood clotting mechanism and wound healing * previous periodontal surgeries in gingival recession areas * pregnancy, lactation,or oral contraceptive drug intake for female patients * insufficient oral hygiene (full- mouth plaque and bleeding scores ≥15% after phase I periodontal treatment) * unchanged traumatic tooth-brushing habit

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

recession depth

Timeframe: change from baseline at following surgery first, third and sixth month respectively

root coverage

Timeframe: change from baseline at following surgery first, third and sixth month respectively

keratinized tissue thickness

Timeframe: change from baseline at following surgery first, third and sixth month respectively

keratinized tissue weight

Timeframe: change from baseline at following surgery first, third and sixth month respectively

clinical attachment level

Timeframe: change from baseline at following surgery first, third and sixth month respectively

Trial details

NCT IDNCT03020732

SponsorGazi University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-02

View on ClinicalTrials.gov More Gingival Recession trials

Plain-language summary

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

recession depth

Timeframe: change from baseline at following surgery first, third and sixth month respectively

root coverage

Timeframe: change from baseline at following surgery first, third and sixth month respectively

keratinized tissue thickness

Timeframe: change from baseline at following surgery first, third and sixth month respectively

keratinized tissue weight

Timeframe: change from baseline at following surgery first, third and sixth month respectively

clinical attachment level

Timeframe: change from baseline at following surgery first, third and sixth month respectively