Safety and Tolerability of Sodium Thiosulfate in Patients With an ACS Undergoing CAG Via Trans-radial Approach.

Inclusion Criteria: * Age ≥ 18 years; * The diagnosis ACS defined by: chest pain suggestive for myocardial ischemia for at least 30 minutes, the time from onset of the symptoms less than 24 hours before hospital admission, with (STEMI) or without (nSTEMI/uAP) an electrocardiogram (ECG) recording with ST- segment elevation of more than 0.1 millivolt (mV) in 2 or more contiguous leads; * PCI via trans-radial approach is being considered as treatment; * Patient is willing to cooperate with the trial during hospitalization Exclusion Criteria: * Known cardiomyopathy or LVEF\<35%; * History of a malignancy treated with chemo- and/or radiotherapy \< 1 year; * Systolic blood pressure under 100 mmHg or over 180 mmHg at presentation; * Cardiogenic shock at presentation * Sedated and/or intubated patients; * Pregnant/breastfeeding at time of presentation * The existence of a condition with a life expectancy of less than 1 year; * A condition which, according to the clinical judgment of the investigator and/or treating physician, does not allow the patient to successfully participate in the study.