Local Changes of Skin Characteristics After an Application of a Topical Product With a Warming or… (NCT03016221) | Clinical Trial Compass
CompletedNot Applicable
Local Changes of Skin Characteristics After an Application of a Topical Product With a Warming or Cooling Effect
Switzerland21 participantsStarted 2017-05-01
Plain-language summary
The use of topical over-the-counter (OTC) products with a warming or cooling effect is widespread in the fields of sport, physiotherapy and in private households. Advertisements for such products promise pain relief when suffering from musculoskeletal disorders such as muscle tension, rheumatism or acute injuries, e.g. sprains. In literature, there are only little information about the efficacy and the physiological mechanisms of topical warming or cooling products. Therefore, the aim of this study is to investigate the local skin characteristics during and after an application of a topical product with a warming or cooling effect.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* no existing musculoskeletal disorders in the region of interest
* no surgery in the region of interest in the last year
* healthy skin conditions in the region of interest
Exclusion Criteria:
* fear of treatment
* regular intake of drugs, excluding contraceptives
* metal implants in the region between C7 and sacrum, including hip joints
* lack of epicritic and protopathic skin sensitivity
* renal insufficiency
* bronchial asthma
* pregnancy/lactation
* type 1 or 2 diabetes mellitus
* polyneuropathy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Local Skin Perfusion
Timeframe: during 45min post application
2
Skin Surface Temperature
Timeframe: At baseline and during 45 minutes post application
3
Local Muscle Tissue Oxygenation
Timeframe: At baseline and during 45 min post application
4
Subjective Temperature Sensation
Timeframe: At baseline and during 45 minutes post application
5
Subjective Thermal Comfort
Timeframe: At baseline and during 45 minutes post application
Trial details
NCT IDNCT03016221
SponsorUniversity of Applied Sciences and Arts of Southern Switzerland