Biomarkers as Predictors of Suicidal Risk in Adolescents

Inclusion Criteria: Suicide Attempt Study Group: * 12-18 years of age * admitted to the Cleveland Clinic inpatient child and adolescent psychiatry unit after suicidal ideations or a suicide attempt Healthy Control Group: * 12-18 years of age * No history of suicide attempt Exclusion Criteria: Suicide Attempt Study Group: * History of autism spectrum disorder * Non-verbal * Moderate or severe intellectual disability (IQ\<70 and patients in special education full-time) * Schizophrenia or schizoaffective disorder diagnosis * Current diagnosis of anorexia or bulimia * History of generalized tonic-clonic epileptic seizures in last 3 months (If patient does not have a history of seizures, and generalized tonic-clonic seizure was clinically determined to be caused by patient's recent overdose attempt, patient can still be recruited for study if 24 hours has passed since last seizure) * History of traumatic brain injury, brain tumor, or any major neurological disorder * Delirium or mood disorder secondary to general medical condition * Current infection, fever, antibiotic use in the last 2 weeks * History of autoimmune or immunodeficiency diseases * Current untreated major endocrine disorder * Current pregnancy or delivery within the last month * Diagnosed malnutrition * Positive urine toxicology for benzodiazepines or opiates on admission * Current substance use disorder diagnosis and referral for CD assessment upon discharge * Current diagnosis of morbid obesity or a current…