Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative (NCT03013621) | Clinical Trial Compass
UnknownNot Applicable
Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative
France30 participantsStarted 2017-01
Plain-language summary
Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context.
The right ventricular dysfunction post cardiopulmonary bypass (CPB) is also a common complication, close to 100% if one takes into account the transient dysfunction.
A recent study showed that right ventricular dysfunction and the IRA seemed related, rather on the slope of venous congestion. We wish to study this phenomenon more specifically in particular to offer reliable diagnostic markers of venous congestion.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age: all major patient
* Gender: both
* Subject has signed an informed consent
* IRA KDIGO stage 1 or urine output \<0.5 mL / kg / h for at least 6 hours / elevation creat\> 26.5μmol / L
* Patient in sinus rhythm at the time of the ultrasound measurements
* No diuretic since intervention
* Absence of circulatory failure (low doses of catecholamines tolerated)
* Extubated: absence of mechanical ventilation
Exclusion Criteria:
* Chronic heart failure right
* Chronic renal failure (GFR \<60)
* Usual treatment with high dose diuretics (furosemide\> 40mg / day)
* Endocarditis
* Emergency surgery (aortic dissection, emergency bypass surgery) / heart surgery D / redux
* Circulatory Support
* ACFA / electro-paced rhythm
* Inability to give informed about information (subject in emergencies, understanding of the subject of difficulty, ...)
* Topic under judicial protection
* Topic guardianship or curatorship
* Pregnancy (women of childbearing age)
* Breastfeeding
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Quantification of sonographic markers of right ventricular