Traditionally known for their role in haemostasis, platelets have also an immune role. Platelets play a key role in immune mediator secretion, and interact with innate and adaptive immune cells, contributing to the fight against pathogens, as viruses. Cytomegalovirus (CMV) is responsible of allograft patients' serious infections, because of the induced immune depression. Platelets activation for patients is not determined during the post-graft period, and platelet induced inflammation following a CMV infection is not described.
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In vitro spontaneous CD62P (P-selectin) expression level
Timeframe: 90 Days
In vitro spontaneous CD63 (membrane protein) expression level
Timeframe: 90 Days
In vitro CD62P (P-selectin) expression level after a CMV antigen stimulation
Timeframe: 90 Days
In vitro CD63 (membrane protein) expression level after a CMV antigen stimulation
Timeframe: 90 Days