UnknownEarly Phase 1

Ischemic Memory Imaging With Myocardial Contrast Echocardiography

United States40 participantsStarted 2018-07-07

Plain-language summary

The overall aim of this study is to determine whether non-invasive imaging with myocardial contrast echocardiography using can provide information on the presence and spatial extent of recent myocardial ischemia by non-invasive echocardiographic imaging.

Who can participate

Age range

19 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

NORMAL CONTROL GROUP Inclusion Criteria: * Normal control individuals Exclusion Criteria: * History of cardiovascular disease (coronary artery disease, MI, peripheral artery disease) * allergy to eggs or ultrasound contrast agents * known or detected right to left shunt * presence of a wall motion abnormality * pregnancy ACS GROUP Inclusion Criteria: * Patients with diagnosis of acute coronary syndrome with either unstable angina or non-ST-elevation MI * Referred for primary percutaneous intervention * At least 1 high risk features (ST changes, positive troponin, wall motion abnormality) Exclusion Criteria: * allergy to eggs or ultrasound contrast agents * hemodynamic instability or shock * known or detected right to left shunt * pregnancy * multivessel CAD requiring multivessel PCI

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Dose optimization

Timeframe: 3 months

Detection of Ischemia

Timeframe: 1 year

Trial details

NCT IDNCT03009266

SponsorOregon Health and Science University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-12

Contact for this trial

Jonathan R Lindner, MD

5034949191 lindnerj@ohsu.edu

View on ClinicalTrials.gov More Myocardial Ischemia trials

Who can participate

Age range

19 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.