Ischemic Memory Imaging With Myocardial Contrast Echocardiography

NORMAL CONTROL GROUP Inclusion Criteria: * Normal control individuals Exclusion Criteria: * History of cardiovascular disease (coronary artery disease, MI, peripheral artery disease) * allergy to eggs or ultrasound contrast agents * known or detected right to left shunt * presence of a wall motion abnormality * pregnancy ACS GROUP Inclusion Criteria: * Patients with diagnosis of acute coronary syndrome with either unstable angina or non-ST-elevation MI * Referred for primary percutaneous intervention * At least 1 high risk features (ST changes, positive troponin, wall motion abnormality) Exclusion Criteria: * allergy to eggs or ultrasound contrast agents * hemodynamic instability or shock * known or detected right to left shunt * pregnancy * multivessel CAD requiring multivessel PCI