CompletedNot Applicable

A Study of Effects of Age and Hyperkyphosis on Spine Motion and Loading

United States41 participantsStarted 2017-04-18

Plain-language summary

We are studying how spine movement changes with age, and when people have vertebral fractures (cracks in the bones of the spine) or hyperkyphosis (a forward stooped posture).

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

No exclusion criteria shall be based on race, ethnicity, or sex. Inclusion Criteria (Non-patient group): * Males and females, ages 18 - 40 years * Able to perform activities such as walking, standing, sitting, bending or lifting without assistance * Willing to sign informed consent form Exclusion Criteria (Non-patient group): • Conditions that might alter thoracic biomechanics: Examples of these include scoliosis, a history of traumatic thoracic injury or spinal surgery, neuromuscular conditions such as Parkinson's disease or muscular dystrophy. * Body mass index \> 30 kg/m2 * Pregnancy * Latex allergies * Currently taking muscle relaxers, steroids, or narcotics * Participation in another research study with radiation exposure * Previous exposure to radiation as part of a medical procedure in the past six months * Musculoskeletal injury or condition that is currently affecting normal activity or movement. Examples of this could include sprains, strains, dislocations or fractures that prevent one from walking, standing, sitting, bending or lifting in a normal manner. Inclusion Criteria (Patient group): * Males and females, ages 75 years and older. * Patients who received a lateral thoracic spine x-ray and had a diagnosis of a vertebral fracture (ICD9 - 805.2) in the year 2011 or later. * At least 6 months since diagnosis of vertebral fracture. * Measurable T4-T12 Cobb angle in lateral thoracic spine x-ray. * Currently living in the Boston area. * Able to perform activit…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Thoracic spine range of motion, in degrees.

Timeframe: Day 1

Trial details

NCT IDNCT03008902

SponsorBeth Israel Deaconess Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-08-31

View on ClinicalTrials.gov More Kyphosis trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.