Outcomes of Surgically Ineligible Patients With Multivessel CAD

Inclusion criteria

• . Participant undergoes coronary angiography revealing unprotected left main stenosis of \> 50%, 3 vessel disease with stenoses \> 70% or 2 vessel coronary disease (\>70%) with one lesion involving the proximal LAD. Patients will also be included if there is FFR evidence of flow limiting stenosis (FFR ≤ 0.80) in the setting of \> 40% angiographic stenosis the left main, 3 epicardial coronaries or 2 vessels including the proximal LAD. Patients with prior bypass surgery will be included if they have ≥ 2 epicardial vascular distributions subtended by a severe native coronary stenosis with either no bypass graft supplying the vessel, a severely diseased (\>70% stenosis) bypass graft supplying the affected vessel or an occluded bypass graft to the affected vessel.
• . Patient considered high risk for coronary artery bypass surgery and declared ineligible for surgery by the heart team.
• . Patient is experiencing clinical symptoms consistent with obstructive coronary artery disease or with evidence of coronary ischemia on non-invasive/invasive (FFR) functional testing.
• . Subject is ≥ 18 years of age at the time of consent and is willing to sign an informed consent document approved by the enrolling hospital's Institutional Review Board and follow-up for 12-months following enrollment in the study