TerminatedNot Applicable

"Natural History" Study of Choroideremia

United States, Canada57 participantsStarted 2016-12

Plain-language summary

The purpose of this study is to understand the rate of progression of all stages of choroideremia using a variety of assessments performed in the clinic including visual field measures, specialized photography of the eye and participant-reported visual problems

Who can participate

Age range18 Years

SexMALE

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Exclusion criteria

✕. Prior therapy with an AAV vector-based treatment
✕. Pre-existing eye conditions that would: (1) preclude future planned treatment in a therapeutic intent clinical trial (i.e. intravitreal injection), (2) interfere with the interpretation of study endpoints, and/ or put patient at risk for surgical complications
✕. Complicating systemic diseases that would preclude future enrollment in a therapeutic intent clinical trial
✕. Any other condition that would not allow the potential subject to complete follow-up examinations during the course of the study and, in the opinion of the investigator, makes the potential subject unsuitable for the study.

What they're measuring

Rate of progression of disease

Timeframe: 4 years

Trial details

NCT IDNCT02994368

Sponsor4D Molecular Therapeutics

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2021-10

View on ClinicalTrials.gov More Choroideremia trials