Active — Not RecruitingNot Applicable

Risk Factors of Medistinal Metastasis in Endoscopic Staging of Lung Cancer

South Korea600 participantsStarted 2016-07

Plain-language summary

The purpose of this study is to investigate risk factors for mediastinal lymph node metastasis in potentially operable non-small cell lung cancer in order to find indications for endoscopic mediastinal staging. Chest CT, integrated PET/CT, and endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) +/- endoscopic ultrasound with bronchoscope-guided fine needle aspiration (EUS-B-FNA) are performed for mediastinal staging. CT and PET/CT findings, histologic types and other risk factors will be analyzed. The investigators develop the prediction method for mediastinal metastasis.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Histologically confirmed or strongly suspected non-small cell lung cancer (NSCLC) * Potentially operable Exclusion Criteria: * M1 disease * Inoperable T4 disease * Mediastinal infiltration or extranodal invasion of the mediastinal lymph node visible on chest CT * Confirmed supraclavicular lymph node metastasis * Pancoast tumours * T1 ground glass opacity nodule (with solid part 1\<cm) * Solid T1 (1\<cm)N0 M0 by CT \& PET/CT * Inoperable patients (after evaluating medical and surgical operability) * Patients who refused surgical treatment * Contraindications for bronchoscopy * Drug reaction to lidocaine, midazolam, fentanyl * Pregnancy

What they're measuring

Relative risk of risk factors for mediastinal metastasis

Timeframe: When confirmative diagnosis are available in all subjects ;3 years

Trial details

NCT IDNCT02991924

SponsorNational Cancer Center, Korea

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2019-12