CompletedNot Applicable

Artificial Shrinkage of Fresh Blastocysts

France150 participantsStarted 2018-05-20

Plain-language summary

The aim of the study is to determine if collapsing an embryo (or making it fold compactly by taking away its fluid) before the transfer in the uterine cavity improves pregnancy rates in assisted reproductive technology (ART). Women coming to our ART center will be randomized in two groups : the collapsing group and a control group. Pregnancy rates will be compared in the two groups. A biomarker (cell free DNA) will also be determined in each group and correlated to pregnancy occurrence.

Who can participate

Age range18 Years – 43 Years

SexFEMALE

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Inclusion Criteria: * Couple eligible for a transfer of a single embryo at the blastocyst stage * Available couple for a follow up of 12 months Exclusion Criteria: * Attempt with frozen embryo or frozen oocyte * Attempt with a pre-implantation diagnosis * Patient has not signed informed consent * Couple in a period of exclusion determined by a previous study * Couple under legal protection, guardianship or guardianship

What they're measuring

Clinical pregnancy rate embryo transfer

Timeframe: 5 weeks

Trial details

NCT IDNCT02988544

SponsorUniversity Hospital, Montpellier

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-08-20

View on ClinicalTrials.gov More Infertility Assisted Reproductive Technology trials