UnknownNot Applicable

Prenatal Screening, Diagnosis and Intrauterine Intervention of Fetal Abnormal Chromosome and Structure in Twins Pregnancy

1,300 participantsStarted 2017-01

Plain-language summary

The risk of abnormal chromosome and structure is much higher in twins than in singletons, and traditional early pregnancy screening strategy for single pregnancy is not suitable for twins. Based on our management experience of fetal medicine at twin pregnancy, and multi-center cooperation, the study will carry out the following clinical studies: 1. to explore a suitable, early, noninvasive and accurate prenatal screening strategy for twin pregnancy. 2. fetal chromosomal abnormalities

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion Criteria: * ultrasound diagnosis as twin pregnancy * at 11-14 gestational weeks Exclusion Criteria: * Multiple pregnancies (three or more) * Maternal history of chromosome aneuploidy abnormality or tumor

What they're measuring

Success rate for the operation

Timeframe: 1 week

Trial details

NCT IDNCT02982356

SponsorShanghai First Maternity and Infant Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-12

View on ClinicalTrials.gov More Chromosome Abnormality trials