TerminatedNot Applicable

Renal Biomarkers to Predict Recovery Following Venoarterial Extracorporeal Membrane Oxygenation

Stopped: insufficient patients to satisfy study protocol(s) inclusion criteria

United States2 participantsStarted 2017-05-01

Plain-language summary

The investigators objective is to assess the utility of renal biomarkers in predicting renal recovery following institution of Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO). Tissue biomarkers of renal injury may provide a real-time indication of renal function and the likelihood of renal recovery in patients having cardiogenic shock and requiring VA-ECMO. In these patients, traditional markers of kidney function (urine output and serum Creatinine level) do not accurately represent renal function.

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age more than 18 years * refractory or advanced cardiogenic shock prior to institution of VA-ECMO Exclusion Criteria: * History of chronic kidney disease prior to cardiogenic shock, as defined by estimated glomerular filtration rate (GFR) less than 60 mL per min * Cognitive impairment * Pregnant women * patient or surrogate is not fluent in English * Long-term immunosuppression

What they're measuring

renal biomarker levels

Timeframe: through VA-ECMO decannulation, an average of 3 weeks

need for continuous renal replacement therapy at hospital discharge (Yes/No)

Timeframe: measured at hospital discharge, an average of 2-3 months following initial hospital admission

Trial details

NCT IDNCT02978378

SponsorMilton S. Hershey Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-03-23

View on ClinicalTrials.gov More Acute Kidney Injury trials