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Pupillometry in Horner's Syndrome

Switzerland135 participantsStarted 2017-02-15

Plain-language summary

Horner's syndrome (HS) is a result of interruption of the sympathetic innervation to the eye and ocular adnexa, which can occur due to carotid artery dissection (CAD), along which the sympathetic nerve fibers travel to reach the eye. Dissection of the carotid artery is one of the etiologies for ischemic stroke in young patients. In our current study, we will explore the diagnostic accuracy of automated binocular pupillometry in the diagnosis or HS, and its potential in identifying dissection of the carotid artery in patients of young age who suffer ischemic stroke.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults 60 years of age or younger * Acute stroke (less than 72 hours from admission) * Informed Consent as documented by signature (Appendix Informed Consent Form) * Ability to understand the study information and consent form Exclusion Criteria: * known history of HS * Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. * Medications affecting pupillary response * History of ocular surgery affecting the pupil

What they're measuring

Finding of pupillary dilation lag using pupillometry in patients with acute stroke due to carotid artery dissection

Timeframe: 1 day of initial visit

Trial details

NCT IDNCT02978079

SponsorUniversity of Zurich

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-31

View on ClinicalTrials.gov More Horner's Syndrome trials