Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy (NCT02971072) | Clinical Trial Compass
CompletedNot Applicable
Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy
United States180 participantsStarted 2014-07
Plain-language summary
The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy. There are three specific aims: (1) determine the effect of acute pain relief on rotator cuff muscle activation in patients with rotator cuff tendinopathy, (2) determine the effect of exercise on rotator cuff muscle activation in patients with rotator cuff tendinopathy, and (3) compare rotator cuff muscle activation between patients with rotator cuff tendinopathy and healthy controls.
Who can participate
Age range
21 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Patient Inclusion Criteria:
* pain with passive provocative maneuvers (positive Hawkins or Neer test)
* pain with active elevation (positive painful arc)
* pain with isometric resisted movements (Jobe's "empty can" test or resisted shoulder external rotation with the arm at the side)
* demonstrate weakness (\>10% force deficit in external rotation)
Patient Exclusion Criteria:
* shoulder surgery on the symptomatic side
* positive Spurling test
* traumatic shoulder dislocation or instability in the past 3 months
* reproduction of shoulder pain with active or passive cervical range of motion
* signs of rotator cuff tear (drop-arm test, lag signs, gross external rotation weakness, or positive image findings)
* current musculoskeletal, neurologic or cardiovascular compromise
Control Inclusion Criteria:
* no current or previous shoulder injury
* matched for age (within 5 years) and sex
* meet Patient Exclusion Criteria (minus musculoskeletal, neurologic, or cardiovascular compromise)
Control Exclusion Criteria:
* pain with active arm elevation
* positive Hawkins, Neer, or Jobe's test
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Rotator cuff activation after subacromial injection and exercise intervention, difference in rotator cuff voluntary activation between subjects and controls
Timeframe: 6 weeks
2
Rotator cuff activation after subacromial injection and exercise intervention, difference in specific rotator cuff muscle activation between subjects and controls