CompletedNot Applicable

Palm And Rice Bran Oil Study

Singapore18 participantsStarted 2016-10

Plain-language summary

The objective of the present study is to compare the effects of liquid or solid state of food on glycaemia, lipaemia and insulinaemia. 25 participants aged between 21 and 45 years will be recruited from the general public in Singapore. Fingerpricks and cannulation may cause minor discomfort and there may be some slight bruising around the site. Fingerpricks and cannulation will be done by an experienced research nurse or a trained research officer to minimize participant discomfort. If bruising does occur, it should disappear within one day and it should not affect participants' regular daily activity. Participants will be limited to a maximum of one test per week. In addition, blood collection will be carried out in a sterile designated area and thus the risk of infection will be very low. On rare occasions, participants may feel unwell during or after the testing session. We have several metabolic suites with beds for these individuals to rest on. The research nurse and research officers will monitor the individuals' condition and they will be provided with a ride home if required. All the study foods will be prepared in a hygienic manner in a purpose-built research kitchen maintained to the highest hygiene standards. The research staff has undergone basic training in food hygiene procedures. Hence, the risk of infective acute gastroenteritis will be minimal. Participants will be provided with some snacks at the end of each testing session. They will also be reimbursed to compensate for their time and costs associated with travel and parking at the completion of the study. In addition, participants will be provided with their blood glucose, blood pressure, and body composition results, with a brief interpretation of these at the conclusion of the study.

Who can participate

Age range

21 Years – 45 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy Chinese male * Age between 21 and 45 years * BMI 18-25 kg/m2 * Body weight \>/=45 kg * Normal Blood Pressure (=140/90 mmHg) * Normal Fasting Blood Glucose (\<6.0 mM) Exclusion Criteria: * People who take part in sports at competitive/endurance levels• * People with major chronic disease such as heart disease, cancer or diabetes mellitus * People who are glucose-6-phosphate dehydrogenase (G-6-PD) deficiency * People who have intolerances or allergies to test products * Individuals who are taking insulin or drugs known to affect glucose metabolism and body fat distribution * People with a major medical or surgical event requiring hospitalization within the preceding three months * Individuals with the presence of disease or drugs which influence digestion and absorption of nutrients * People who are on any therapeutic diet/ drug therapy * Smokers

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in postprandial blood glucose over 180 minutes period

Timeframe: 180 minutes

Change in postprandial serum triglyceride over 360 minutes period

Timeframe: 360 minutes

Change in postprandial serum glucose over 360 minutes period

Timeframe: 360 minutes

Trial details

NCT IDNCT02969057

SponsorSingapore Institute of Food and Biotechnology Innovation

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2017-10

View on ClinicalTrials.gov More Glucose Response trials