EGESTA - Emergent GI Therapy for Severe, Complicated CDI Using Fecal Microbiota Transplant

Inclusion Criteria: * Adults between 18 years of age and 75 years of age. * Have CDI defined as clinical symptoms of CDI (diarrhea with or without abdominal pain/abdominal distention) with a confirmatory nucleic acid amplification test (NAAT) positive for CDI. * Have severe/complicated disease as defined by ACG guidelines(appendix 1), with any of the following attributable to CDI: * Admission to intensive care unit for CDI * Hypotension (systolic blood pressure \< 90 mmHg) with or without required use of vasopressors * Fever ≥ 38.5 ° C * Ileus (as defined by the absence of intestinal function for at least 24 hours and/or radiographic evidence of pathologically dilated small intestine without evidence of a mechanical obstruction) or significant abdominal distention * Mental status changes * WBC ≥ 35,000 cells / mm 3 or \< 2,000 cells / mm 3 * Serum lactate levels \>2.2 mmol / l * End organ failure (mechanical ventilation,renal failure as defined by a rise in creatinine of \>1.5 mg/dL either above the upper limit of normal for creatinine, or \> 1.5 mg/dL from premorbid levels if that information is known, acute hepatic dysfunction as defined by an increase in AST or ALT to twice the upper limit of normal, etc.) Exclusion Criteria: * Pregnant or lactating women * Prisoners * Patients under the age of 18 or over the age of 76 years of age * Patients who are immunocompromised including but not limited to: * Have HIV infection historically reported, regardles…