CompletedNot Applicable

Exercise and Cognition Trials

United States60 participantsStarted 2016-08-01

Plain-language summary

The purpose of this study is to determine whether an acute bout of exercise may temporarily enhance cognitive function (such as memory or attention span) by measuring behavioral performance on cognitive tests, as well as expression of hormones in circulation associated with brain plasticity and stress.

Who can participate

Age range18 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Body mass index (BMI) of between 18.5 and 35 kg/m2 * Normal or corrected-to-normal vision * No contraindications to participation in moderate to hard intensity physical activity Exclusion Criteria: * Self-report of alcohol or substance abuse in the past year or current treatment * Women who are pregnant or nursing * BMI of \< 18.5 or \> 35 kg/m2 * Diabetes mellitus. Subjects will be excluded for diabetes even if controlled by medications * Cigarette smoking in the previous 12 weeks * Elevated blood pressure (BP) defined as systolic BP ≥ 140 mm Hg or diastolic BP ≥ 90 mm Hg * Self-report of cardiovascular disease, cancer, renal disease, and other serious conditions that could be exacerbated by moderate intensity physical activity.

What they're measuring

visual short-term memory questionnaire

Timeframe: baseline

visual short-term memory questionnaire

Timeframe: up to 5 minutes post intervention

visual short-term memory questionnaire

Timeframe: 1 hour after intervention

visual short-term memory questionnaire

Timeframe: 2 hours after intervention

visual short-term memory questionnaire

Timeframe: 24 hours after baseline

visual long-term memory questionnaire

Timeframe: 24 hours after baseline

verbal fluency

Timeframe: baseline

verbal fluency

Timeframe: up to 5 minutes post intervention

Trial details

NCT IDNCT02958735

SponsorJohns Hopkins University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-05-02

View on ClinicalTrials.gov More Alteration of Cognitive Function trials

Plain-language summary

Who can participate

Age range18 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

visual short-term memory questionnaire

Timeframe: baseline

visual short-term memory questionnaire

Timeframe: up to 5 minutes post intervention

visual short-term memory questionnaire

Timeframe: 1 hour after intervention

visual short-term memory questionnaire

Timeframe: 2 hours after intervention

visual short-term memory questionnaire

Timeframe: 24 hours after baseline

visual long-term memory questionnaire

Timeframe: 24 hours after baseline

verbal fluency

Timeframe: baseline

verbal fluency

Timeframe: up to 5 minutes post intervention