CompletedPhase 1

Vietnam Cryptococcal Retention in Care Study (CRICS) Federal Financial Report

Vietnam1,177 participantsStarted 2015-06

Plain-language summary

CRICS financial report for the first budget year of the study

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged ≥ 18 years * Confirmed HIV infection using National Testing Algorithm * CD4 ≤100 cells/μL * Able to provide written informed consent Exclusion Criteria: * History of prior CM * Receipt of systemic antifungal medication for more than 4 consecutive weeks within the past 6 months * Currently taking ART or history of ART for more than 4 weeks within the past year * Known to be currently pregnant or planning to become pregnant during the study period

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The proportion of patients who have advanced HIV disease (CD4 <100)

Timeframe: 12 months

Prevalence of CrAg-positivity among HIV patients with advanced disease

Timeframe: 12 months

The proportion of patients who have no new opportunistic infections at 12 months

Timeframe: 12 months

Mortality rate among HIV patients with advanced disease

Timeframe: 12 months

Trial details

NCT IDNCT02955862

SponsorNational Hospital for Tropical Diseases, Hanoi, Vietnam

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2017-09

View on ClinicalTrials.gov More Cryptococcal Meningitis trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

The proportion of patients who have advanced HIV disease (CD4 <100)

Timeframe: 12 months

Prevalence of CrAg-positivity among HIV patients with advanced disease

Timeframe: 12 months

The proportion of patients who have no new opportunistic infections at 12 months

Timeframe: 12 months

Mortality rate among HIV patients with advanced disease

Timeframe: 12 months