CompletedNot Applicable

A Study Examining Adolescents With Non-Suicidal Self-Injury

United States168 participantsStarted 2016-08

Plain-language summary

This study will examine longitudinal brain development in young adolescent girls with a history of Non-Suicidal Self-Injury (NSSI). Specifically, three constructs outlined by the Research Domains Criteria (RDoC) will be examined through self-assessment, MRI, and a cognitive battery.

Who can participate

Age range12 Years – 16 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 12-16 years old * Female * Has had first menstruation * Willingness to have de-identified data shared with RDoC database Inclusion Criteria - Adolescents with Non-Suicidal Self-Injury: * Any history of self harm Inclusion Criteria - Healthy Controls: * No history of self harm Exclusion Criteria: * Male * Pregnancy * MRI Incompatibility * IQ of less than 80 * Major Medical Illness * Diagnosis of any of the following: Primary Psychotic Disorder, Bipolar Spectrum Disorder, Autism Spectrum Disorder, Current or Past Substance Use Disorder

What they're measuring

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Lifetime Episodes

Timeframe: Baseline

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Year Episodes

Timeframe: Baseline

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Month Episodes

Timeframe: Baseline

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Lifetime Episodes

Timeframe: Month 12

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Year Episodes

Timeframe: Month 12

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Month Episodes

Timeframe: Month 12

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Lifetime Episodes

Timeframe: Month 24

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Year Episodes

Timeframe: Month 24

Trial details

NCT IDNCT02947308

SponsorUniversity of Minnesota

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-07-18

Results submitted2025-09-23

View on ClinicalTrials.gov More Self-Injurious Behavior trials

Who can participate

Age range12 Years – 16 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Lifetime Episodes

Timeframe: Baseline

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Year Episodes

Timeframe: Baseline

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Month Episodes

Timeframe: Baseline

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Lifetime Episodes

Timeframe: Month 12

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Year Episodes

Timeframe: Month 12

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Month Episodes

Timeframe: Month 12

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Lifetime Episodes

Timeframe: Month 24

Self-Injurious Thoughts and Behaviors Interview (SITBI) - Past Year Episodes

Timeframe: Month 24