WithdrawnNot Applicable

Changes in Central Arterial Pressure When Comparing ACOG Hypertensive Urgency Protocols

Stopped: PI withdrew the protocol

0Started 2016-08

Plain-language summary

The investigators plan to monitor the central blood pressure in women with severely elevated blood pressures (160/110) in pregnancy in the acute setting. Currently ACOG recommends 3 different options for blood pressure control, however no one has studied how these medications affect the central pressures, only peripheral blood pressure.

Who can participate

Age range14 Years – 50 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pregnant women * Singleton pregnancy * Severe hypertension as defined by a blood pressure of 160/110 with plans to treat Exclusion Criteria: * Multiple pregnancy * Blood pressures \< 160/110, or those whose blood pressures do not require medication for control * Irregular heart rhythms or arrhythmias * Peripheral arterial disease, leg artery disease * Reynaud's phenomena * Intense cold/hypothermia * If there is a wound at location of where central arterial cuff would be placed or tonometer for carotid assessment * Known sensitivity to labetalol, nifedipine, or hydralazine * Severe tachycardia (\>120) * Greater than 1st degree heart block * Severe asthma * Congestive heart failure or heart disease * Lupus * Inability to adequately monitor BP * Inability to monitor fetus (if 23 weeks or above) * Magnesium started prior to initiation of study

What they're measuring

medication recommended by ACOG for severe hypertension

Timeframe: 20min from time of first normal blood pressure after intervention

Trial details

NCT IDNCT02933593

SponsorSt. Louis University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-01

View on ClinicalTrials.gov More Hypertension trials