CompletedNot Applicable

Prostatic Artery Embolization Before Radical Prostatectomy in Prostate Cancer: A Proof-of-concept Study

Switzerland12 participantsStarted 2016-09

Plain-language summary

MRI findings after successful PAE in patients suffering from BPH suggest a complete necrosis of the prostate after this intervention. Thus, PAE might also play a role in the treatment of prostate cancer. This proof of concept study assess the impact of PAE in patients with proven prostate cancer.

Who can participate

Age range45 Years – 75 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Men 45 - 75 years old undergoing RALP * Patient has biopsy-proven prostate adenocarcinoma * Localized disease (tumorstage cT1-cT2), assessed by clinical and MRI findings * Written informed consent Exclusion Criteria: * Severe atherosclerosis * Severe tortuosity or ectasia in the aortic bifurcation or internal iliac arteries * Tumor stage \> cT2 assessed by clinical and MRI findings * Allergy to intravenous contrast media * Contraindication for MRI imaging * Renal failure (GFR\<60ml/min) * History of pelvic irradiation or radical pelvic surgery

What they're measuring

Tumor response

Timeframe: 6 weeks after PAE (at the time of RALP)

Trial details

NCT IDNCT02917161

SponsorDominik Abt

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-06

View on ClinicalTrials.gov More Prostate Cancer trials