TerminatedPhase 4

Acute Unilateral Vestibulopathy and Corticosteroid Treatment

Stopped: Placebo medication expired

Sweden78 participantsStarted 2015-12

Plain-language summary

Randomized placebo controlled trial on patients suffering from acute unilateral vestibulopathy. Patients will be randomized into 3 arms; 1) Placebo only, 2) Short corticosteroid treatment (3days) 3) Longer corticosteroid treatment (11 days). Vestibular function as well as subjective symptoms will be estimated in the acute stage and regularly up to one year after the debut.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * definite unilateral vestibulopathy * no pathological HINTS (examination criteria in acute vestibular syndrome) * capable of making their own decisions Exclusion Criteria: * tinnitus or hearing loss with same debut as vertigo * history of bleeding peptic ulcer * glaucoma * pregnancy or non-acceptance to use anticonception measures during 13 days after debut * high blood pressure \>180 systolic, 105, diastolic * ketoacidosis with a Base Excess \>=2 * psychic disorder (not including mild depression) * serious infection (neutropenia, tuberculosis) * chronic otitis * history of vertiginous disease; Ménière, Vertiginous migraine, atypical BPPV

What they're measuring

Caloric function

Timeframe: after 3 months

Caloric function

Timeframe: 1 year

Trial details

NCT IDNCT02912182

SponsorLund University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-03-01

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