Lipoic Acid Supplement for Cystine Stone

Inclusion Criteria: * Documented cystinuria on prior 24-hour urine collection and/or stone analysis; history of previous cystine kidney stones. * Being able and willing to provide consent. Exclusion Criteria: * Poorly controlled diabetes mellitus (hemoglobin A1C \> 8.0% for more than 1 year). * Current alpha-lipoic acid administration at the time of screening or within the last year prior to screening. * Vulnerable populations including incarceration status. * Unable to give informed consent. * Non-English primary language. * Pregnancy, lactation, or child-bearing age without birth control devices. * Anticipation of pregnancy during the study period. * Serious illness likely to cause death within the next 5 years.