CompletedPhase 4

Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest

Slovenia60 participantsStarted 2013-09

Plain-language summary

The purpose of this study is to determine whether there is potential benefits of prophylactic antibiotic treatment in comatose survivors of out-of-hospital cardiac arrest (OHCA) treated in intensive care unit with therapeutic hypothermia.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female and male over 18 years old * Comatose survivors of out-of-hospital cardiac arrest treated in intensive care unit with therapeutic hypothermia Exclusion Criteria: * Suspected or confirmed pregnancy * Allergy to amoxicillin-clavulanic acid * Tracheobronchial aspiration * Antibiotic therapy before cardiac arrest * Need of antibiotics due to other causes * Candidates for immediate veno-arterial extracorporeal membrane oxygenation (VA ECMO) * Patients in whom no active treatment was decided on admission

What they're measuring

Value of C-reactive protein (CRP) at day three

Timeframe: Three days after admission to Intensive care unit (ICU)

Trial details

NCT IDNCT02899507

SponsorUniversity Medical Centre Ljubljana

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-03

View on ClinicalTrials.gov More Out-of-hospital Cardiac Arrest trials