TerminatedNot Applicable

Coronary Artery Disease (CAD) in Suppressed HIV-infected

Stopped: Departure of the coordinating investigator

France62 participantsStarted 2017-03-01

Plain-language summary

HIV-infected patients with intermediate-high risk have a high prevalence of CAD and a substantial proportion of obstructive CAD. Degree of stenosis is associated with immunoactivation (lymphocyte and monocyte) and microbial translocation

Who can participate

Age range48 Years – 100 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: HIV-infected patients \>= 45 years with 2 or more CV risk factors currently on ART HIV-RNA \< 50 copies \>= 12 months (one blip allowed) Asymptomatic regarding cardiac symptoms (chest pain, syncope, dyspnea) Stable ART for more than 6 months Exclusion Criteria: Previous CV event (MI, stroke, unstable angina, CABG) Atrial fibrillation Chronic kidney disease \[eGFR \< 60ml/min MDRD or CKD-Epi) Unstable liver disease History of IV contrast allergy Chronic inflammatory disorders apart from HIV

What they're measuring

coronary computed tomographic angiography (CCTA)

Timeframe: 1 month

Trial details

NCT IDNCT02898896

SponsorUniversity Hospital, Montpellier

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-01-05

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