Fracture Healing Assessed by HR-pQCT After Administration of Calcium and Vitamin D

Inclusion Criteria: * Postmenopausal women older than 50 years who present themselves in clinic with a distal radius fracture due to a trauma. * Patients with a stable distal radius fracture treated by cast immobilization. * Patients who understand the conditions of the study and are willing and able to comply with the scheduled biochemical and radiographic evaluations and the prescribed rehabilitation. * Patients who signed the Ethics Committee approved specific Informed Consent Form prior to inclusion. Exclusion Criteria: * Patients who underwent surgery of the wrist or radius on a previous occasion on the same side or who need surgery this time. * Patients with active or suspected infection such as pneumonia or complicated urinary tract infection in the last 3 months. * Patients with malignancy or a pathological fracture in the last 12 months. * Patients with a neuromuscular or neurosensory deficit, e.g. Parkinson's disease, which would limit the ability to assess the performance during the healing period. * Patients with known systemic or metabolic disorders leading to progressive bone deterioration, such as: hyperthyroidism, hyperparathyroidism, chronic kidney disease with eGFR\<30 ml/min, sarcoidosis, hypercalcemia, * Patients with an active inflammatory disease during the last year such as rheumatoid arthritis, systemic lupus erythematous, inflammatory bowel disease, e.g. Crohn's disease and ulcerative colitis. * The use of glucocorticoids during the last 12 months.…