The study is a prospective birth cohort study and the purpose is to describe the status of maternal key nutrients(eg. folate and vitamin D) supplementation among pregnancies at early gestation in Shanghai, to find out the association between the level of serum key nutrients and atopic dermatitis (AD) in offsprings during 6 months.
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Infant atopic dermatitis
Timeframe: incident of AD during 6 months after birth, diagnosis confirmed based on disease history till 12 months