CompletedNot Applicable

Ultrasound Diagnostic for Diaphragmatic Dysfunction in Reanimation

France74 participantsStarted 2015-03-06

Plain-language summary

Extubation is a crucial step when patients are being weaned from mechanical ventilator support. Indeed, the patient has to face an increasing burden imposed to the ventilation system. The ability to overcome this event will determine the patient survival. A warning signal could be very useful is this situation. 2 recent studies have shown that measuring diaphragmatic cupolas and muscular fibers thickening fraction could help to spot a population with a high risk of "diaphragmatic weakness", characterized by a high failure extubation rate. This study aims to verify that this kind of group of patients does exist.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Successful spontaneous breathing trial and extubation expected on the same day and 1 of the following criteria : * Age \> 65 * Mechanical ventilation during \> 7 days * Cardiac history (ischemic, rhythmic or valve cardiopathy) * Respiratory history (documented or likely chronic respiratory failure) Exclusion Criteria: * Patient who is tracheotomized * Peripheric neuromuscular disease (myasthenia, myopathy) * Surgery circumstances that could affect the quality of the ultrasound exam (drains or bandages) * Pregnant woman * Age \< 18

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Extubation success rate

Timeframe: 7 days after the reported extubation

Trial details

NCT IDNCT02883465

SponsorCentre Hospitalier Saint Joseph Saint Luc de Lyon

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-10-28

View on ClinicalTrials.gov More Mechanical Ventilation Weaning trials