CompletedNot Applicable

Effect of Dose-dependent Platelet Rich Fibrin(PRF)

21 participantsStarted 2014-04

Plain-language summary

Miller Class I Gingival Recessions (GR) have been treated by using Coronally Advanced Flap (CAF) with Platelet Rich Fibrin membrane (PRF membrane) or Connective Tissue Graft (CTG). The aim of this study was to evaluate the effect of different multiple layers of PRF membranes for the treatment of GR and compare the results with CTG procedure.

Who can participate

Age range

18 Years – 52 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Periodontally and systemically healthy patient, ≥ 18 years.
. Miller Class I gingival recession at the buccal aspect of lower and upper incisors, canines or premolars.
. The presence of ≥ 2 mm keratinized tissue apical to the recession.
. The presence of identifiable cemento enamel junction (CEJ).
. ≤ 2 mm probing depth (PD)

Exclusion criteria

. Smoking
. Pregnancy
. Periodontal surgery in the past six months.
. Caries, deep abrasion, restoration or pulpal pathology on the involved tooth.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change from baseline clinical measurement of gingival depth and gingival recession by periodontal Williams Type Probe as millimeter at postoperative 6 month

Timeframe: before surgery and following surgery sixth month

Change from baseline measurement of keratinized tissue thickness on defects region by spreader and digital calliper at 6 months

Timeframe: before surgery and following surgery sixth month

Change from baseline measurement root coverage at 6 months in millimeters by periodontal probe and change from baseline measurement of root coverage percentage using calculate formula at 6 months

Timeframe: before surgery and following surgery sixth month

Trial details

NCT IDNCT02882464

SponsorGazi University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-02

View on ClinicalTrials.gov More Gingival Recession trials

Plain-language summary

Who can participate

Age range

18 Years – 52 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Periodontally and systemically healthy patient, ≥ 18 years.
. Miller Class I gingival recession at the buccal aspect of lower and upper incisors, canines or premolars.
. The presence of ≥ 2 mm keratinized tissue apical to the recession.
. The presence of identifiable cemento enamel junction (CEJ).
. ≤ 2 mm probing depth (PD)

Exclusion criteria

. Smoking
. Pregnancy
. Periodontal surgery in the past six months.
. Caries, deep abrasion, restoration or pulpal pathology on the involved tooth.

What they're measuring

Change from baseline clinical measurement of gingival depth and gingival recession by periodontal Williams Type Probe as millimeter at postoperative 6 month

Timeframe: before surgery and following surgery sixth month

Change from baseline measurement of keratinized tissue thickness on defects region by spreader and digital calliper at 6 months

Timeframe: before surgery and following surgery sixth month

Change from baseline measurement root coverage at 6 months in millimeters by periodontal probe and change from baseline measurement of root coverage percentage using calculate formula at 6 months

Timeframe: before surgery and following surgery sixth month