The Utility of Radiotherapy in the Management of Haemoptysis Secondary to Aspergillomata and Structural Lung Diseases

Inclusion Criteria: * Adult subjects, 18 years of age and older. * Written informed consent provided by patient * Current or previously documented admission to hospital with large volume haemoptysis (\>200ml); or haemoptysis with haemodynamic compromise (SBP \< 100mmHg for 15 minutes) or requiring fluid resuscitation; haemoptysis requiring intubation or deemed life-threatening by attending clinicians. * The cause of haemoptysis must be due to severe underlying lung destruction/ bronchiectasis, post-tuberculous lung damage or the presence of an aspergillomata. * Primary bronchial artery embolisation not considered technically possible or failed BAE * Lung resection not possible because of poor cardiopulmonary reserves (as defined by the current ERS/ESTS clinical guidelines, independently reviewed by a team of consisting of a thoracic surgeon, pulmonologist and anaesthetist who will need to be in agreement on inoperability and/or lack of cardiopulmonary reserve) Exclusion Criteria: * Active tuberculosis * High clinical suspicion of lung carcinoma * Known deep venous thrombosis or pulmonary embolism * Any social or psychological condition that may impair insight or compliance with the study including follow up * Any other condition, which in the opinion of the investigators, places the subject at increased risk for transport and administration of EBRT e.g. severe haemodynamic instability, mechanical ventilation with high FiO2 requirements etc.