UnknownNot Applicable

Different Glaucoma Treatments Effect on Intraocular Pressure Fluctuation With Postural Change in Eyes With Open-angle Glaucoma

150 participantsStarted 2016-09

Plain-language summary

The purpose of this study is to investigate the effect of trabeculectomy, glaucoma drainage devices, cyclophotocoagulation and ocular hypotensive eye-drops on IOP elevation with postural change from the sitting to supine positions in eyes with open-angle glaucoma. Patients will be assigned to the different study groups according to their past ocular history. Interventions are similar to all study group and no medical therapy alteration will be made.

Who can participate

Age range18 Years – 95 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * OAG patients * Ocular Hypertension (OHT) patients * Healthy subjects, without any ocular pathology (except for refraction errors, past cataract surgery, strabismus or amblyopia). Exclusion Criteria: * Other intraocular surgeries within the past 3 months * Illness effecting episcleral venous pressure, such as superior vena cava syndrome, thyroid eye disease, orbital masses * Patients who are unable to maintain supine position for 15 minutes * Corneal abnormalities: epithelial pathologies, corneal infection, corneal erosions, corneal scars, keratoconus, S/P corneal transplantation (lamellar/full thickness) * Hypersensitivity to oxybuprocaine hydrochloride

What they're measuring

Measurements of Intra Ocular Pressure Fluctuation with Postural Change in Eyes with Open-angle Glaucoma and Ocular Hypertension, compared to healthy subjects

Timeframe: Change from baseline 5 minutes following position change

Trial details

NCT IDNCT02868502

SponsorMeir Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-08

Contact for this trial

Ortal Fogel Tempelhof, M.D

+972528518303 talifog@gmail.com