CompletedNot Applicable

Effect of Non-surgical Periodontal Therapy on Gingival Crevicular Fluid Interleukin-21 Levels

34 participantsStarted 2014-04

Plain-language summary

Human IL-21 is present in gingival crevicular fluid in periodontal health, gingivitis and chronic periodontitis. A significant increase in the concentration of IL-21 in gingival crevicular fluid is observed with an increase in the amount of periodontal destruction. Non- surgical periodontal therapy aided in decrease of GCF IL-21 levels in clinical gingivitis and chronic periodontitis

Who can participate

Age range20 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients having more than or equal to 14 functional teeth, systemically healthy patients who had not received any form of surgical and non surgical periodontal therapy or received antibiotics or non-steroidal anti-inflammatory Exclusion Criteria: * smokers pregnant females

What they're measuring

Pocket Depth

Timeframe: 6 weeks

Gingival Index

Timeframe: 6 weeks

Plaque Index

Timeframe: 6 weeks

Relative Attachment Level:

Timeframe: 6 weeks

Interleukin-21(IL-21) Cytokine Levels

Timeframe: 6 weeks

Trial details

NCT IDNCT02861937

SponsorKrishnadevaraya College of Dental Sciences & Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-09

Results submitted2017-05-17

View on ClinicalTrials.gov More Chronic Peridontitis Patients trials