CompletedNot Applicable

The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients

South Korea10 participantsStarted 2016-05-31

Plain-language summary

ECMO(Extracorporeal membrane oxygenation) is being essential for cardiopulmonary failure patients. There are two types of ECMO, which is veno-veno (V-V) that can be used in respiratory failure patients and veno-arterial (V-A) that can be used in cardiac failure patients. V-A ECMO can also be used during lung transplantation, substitution of cardiopulmonary bypass, which can show sufficient performance during operation and better postoperative outcome. However, regarding V-A ECMO circulating from femoral vein to femoral artery, there is a pro blem of differential hypoxia which might influence coronary artery and head vessels. In this prospective study, the investigators are planning to put another ECMO catheter into internal jugular vein which takes a role of left to right shunt, to mitigate the hypoxia of coronary artery.

Who can participate

Age range

20 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

. patients who have history of coronary artery occlusive disease
. patients with arrhythmia

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

arterial blood oxygen partial pressure (PaO2)

Timeframe: 5 min after jugular catheter flow 0ml/min

arterial blood oxygen partial pressure (PaO2)

Timeframe: 5 min after jugular catheter flow 500 ml/min

arterial blood oxygen partial pressure (PaO2)

Timeframe: 5 min after jugular catheter flow 1,000ml/min

arterial blood oxygen partial pressure (PaO2)

Timeframe: 5 min after jugular catheter flow 1,500ml/min

Trial details

NCT IDNCT02859194

SponsorYonsei University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-10-14

View on ClinicalTrials.gov More Interstitial Pulmonary Fibrosis ARDS trials

Plain-language summary

What they're measuring

arterial blood oxygen partial pressure (PaO2)

Timeframe: 5 min after jugular catheter flow 0ml/min

arterial blood oxygen partial pressure (PaO2)

Timeframe: 5 min after jugular catheter flow 500 ml/min

arterial blood oxygen partial pressure (PaO2)

Timeframe: 5 min after jugular catheter flow 1,000ml/min

arterial blood oxygen partial pressure (PaO2)

Timeframe: 5 min after jugular catheter flow 1,500ml/min