CompletedNot Applicable

Lung MRI and Allergic Broncho-pulmonary Aspergillosis in Cystic Fibrosis

France240 participantsStarted 2014-01

Plain-language summary

In this diagnostic study, the aim is at evaluating the diagnostic accuracy of MRI (Magnetic Resonance Imaging) to detect allergic broncho-pulmonary aspergillosis in patients with cystic fibrosis.

Who can participate

Age range6 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Cystic fibrosis proven by sweat chloride and genetic tests * Age superior or equal to 6 year-old * Diagnosis of ABPA available on the basis of the criteria by Cystic Fibrosis Foundation Consensus Conference * No contraindication to perform MRI Non-Inclusion Criteria: . Age inferior to 6-year-old * Cystic fibrosis not proven * ABPA status not documented * MRI contraindications: Pregancy, Magnetically activated implanted devices (cardiac pacemakers, insulin pumps, neurostimulators, cochlear implants...), metal inside the eye or the brain (aneurysm clip, ocular foreign body not compatible with MRI), cardiac valvular prothesis not compatible with MRI, subject with claustrophobia. Exclusion Criteria: None

What they're measuring

Diagnostic accuracy of lung MRI for ABPA in CF owing to increased T1 and decreased T2 signal intensity of mucus

Timeframe: From date of inclusion until the date of final ABPA status diagnosis, assessed up to 12 months

Trial details

NCT IDNCT02853175

SponsorHôpital Haut Lévêque

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-01

View on ClinicalTrials.gov More Pulmonary Cystic Fibrosis trials