Active — Not RecruitingPhase 3

Consolidation Chemotherapy for Locally Advanced Mid or Low Rectal Cancer After Neoadjuvant Concurrent Chemoradiotherapy

South Korea358 participantsStarted 2016-12-07

Plain-language summary

This trial is to assess the efficacy and feasibility of consolidation chemotherapy after neoadjuvant chemoradiotherapy for locally advanced mid or low rectal cancer.

Who can participate

Age range

20 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Histologically confirmed adenocarcinoma of mid or low rectum
. Locally advanced rectal cancer confirmed by image (i.e. Magnetic resonance image)
. ECOG performance status of 0-2
. ASA grade ≤ 3
. An informed consent has been signed by the patient

Exclusion criteria

. Upper rectal cancer
. Clinical stage T1or2N0 on MRI
. Clinical stage T4Nany on MRI
. Clinical stage TanyNanyM1 by image or histology
. The patient received chemotherapy or radiotherapy during the past 6 months
. The patient received any therapy for colorectal cancer or another malignancy during the past 5 years
. The patient has severe underlying diseases or poor condition to receive chemotherapy or radiotherapy

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pathologic complete response

Timeframe: 2 years

Disease-free survival

Timeframe: 3 years

Trial details

NCT IDNCT02843191

SponsorKyung Hee University Hospital at Gangdong

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-15

View on ClinicalTrials.gov More Rectal Cancer trials