The Effect of Pre-treatment Biopsy for Non-neoplastic Renal Disease vs no Biopsy on Estimated Glomerular Filtration Rate in Patients With Small Renal Mass: a Single-center, Single-blinded, Randomized, Parallel Group Clinical Trial

Inclusion Criteria: * Age 18 or greater * Scheduled for renal biopsy as part of clinical care * Diagnosis of small renal mass (\< 4cm) based on imaging (CT, MRI, Ultrasound, or other) * Patient must provide written, informed consent for study procedures before randomization * Renal mass must be primarily solid (as opposed to cystic) in nature Exclusion Criteria: * Patients less than 18 years of age * Patients who are prisoners * Women who are pregnant-self reported * Patients with Bosniak 3 or 4 cystic renal masses * Patients with history of renal transplantation * Patients with eGFR less than 30-based on review of clinical labs * Patients on dialysis * Patients with bleeding disorders