Stopped: Reached scientific goals, further recruitment would not further advance the findings of study.
Surgery on the gastrointestinal (GI) tract results in profound changes to the metabolic profile. This is well described, including the rapid resolution of diabetes seen after bariatric surgery. The underlying pathophysiology, and incidence in lean patients undergoing surgery for cancer, is somewhat less described. The investigators plan to assess the symptomatic and glycaemic profile, as well as causative pathways, for metabolic symptoms in patients after surgery on the GI tract. The investigators will use glucose tolerance tests, physiological challenges with somatostatin analogues and antibiotics, and assess tissue transcriptomic changes.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Severity of hypoglycaemia during glucose tolerance test as measured by plasma glucose levels
Timeframe: Glucose tolerance test immediately after drug intervention