TerminatedNot Applicable

Description of Individual Radiosensitivity With Molecular Biomarkers in a Pediatric Oncology Population

Stopped: The liquidation of our industrial partner NEOLYS Diagnostics, directly involved in the methodology of the study and a sub-optimal rate of inclusions which did not allow us to include all patient within the allotted time.

France40 participantsStarted 2017-03-13

Plain-language summary

This study aims to explore prospectively the distribution of individual radiosensitivity in the pediatric population and to determine the predictive power of individual radiosensitivity biomarkers from an immunofluorescence technique on primary dermal fibroblasts

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children \< 18 years old * Patient with an indication of radiotherapy * Patient must be affiliated to a social security system * Patient under parental autority * Ability to provide an informed written consent form Exclusion Criteria: * Contraindications for skin biopsy * Contraindications for radiotherapy * Referred to palliative radiotherapy * Prior radiotherapy in the same area * Indication of hypofractionated radiotherapy * Patient monitoring impossible * Patients deprived of liberty or under supervision

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

skin fibroblast radiosenstivity

Timeframe: up to 5 months

Trial details

NCT IDNCT02827552

SponsorInstitut de Cancérologie de Lorraine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-02-07

View on ClinicalTrials.gov More Cancer-related Problem/Condition trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.